Drug Facts & Side Effects. GENERIC NAME: estradiol. BRAND NAME: Alora, Climara, Delestrogen, Depo- Estradiol, Divigel, Elestrin, Estrace, Estrasorb, Estrogel, Evamist, Femring, Menostar, Minivelle, Vivelle, Vivelle- Dot. Climara (Estradiol) and/or alternatives. To apply the Climara skin patch, you must place the adhesive side onto a clean and dry section of your lower abdomen or onto the upper area of your buttocks. Easy to read patient leaflet for Climara weekly patch. Includes indications, proper use, special instructions, precautions, and possible side effects.
DRUG CLASS AND MECHANISM: Estrogen is one of the major female hormones, the other one being progesterone. Estrogens occur in nature in several chemical forms. In women with. active menstrual cycles, the ovaries produce between 7. This is converted to estrone and to a lesser extent estriol. After menopause, estrone made in the adrenal glands, is the most active circulating estrogen. Estrogens cause growth and development of female sex organs and maintain sex characteristics, including underarm and pubic hair and the shape of body contours and skeleton. Estrogens also increase secretions from the cervix and growth of the inner lining of the uterus (endometrium). Estrogens reduce LDL- cholesterol (. Estrogens, when taken alone or in combination with a progestin (progesterone), have been shown to reduce the risk for hip fracture due to osteoporosis by 2. PRESCRIBED FOR: Estradiol is prescribed for symptomatic treatment of the usual symptoms associated with menopause (hot flashes. Visit the FDA Med. Watch website or call 1- 8. Daily. Med - CLIMARA- estradiol patch. Patient Information. Climara (Kl. There may be new information. This information does not take the place of talking to your healthcare provider about your menopausal symptoms or your treatment. What is Climara? Climara is a prescription medicine patch (Transdermal System) that contains estradiol (an estrogen hormone). What is Climara used for? The Climara is used after menopause to. The ovaries normally stop making estrogens when a woman is between 4. This drop in body estrogen levels causes the . Sometimes, both ovaries are removed during an operation before natural menopause takes place. The sudden drop in estrogen levels causes . In some women, the symptoms are mild, and they will not need to use estrogens. In other women, symptoms can be more severe. You and your healthcare provider should talk regularly about whether you still need treatment with Climara. If you use Climara only to treat your menopausal changes in and around your vagina, talk with your healthcare provider about whether a topical vaginal product would be better for you. You and your healthcare provider should talk regularly about whether you still need treatment with Climara. Your healthcare provider should check any unusual vaginal bleeding to find out the cause. If you have or have had cancer, talk with your healthcare provider about whether you should use Climara. If you think you may be pregnant, you should have a pregnancy test and know the results. Do not use Climara if the test is positive and talk to your healthcare provider. Your healthcare provider should check any unusual vaginal bleeding to find out the cause. Some medicines may affect how Climara works. Climara may also affect how your other medicines work. Keep a list of your medicines and show it to your healthcare provider and pharmacist when you get new medicine. How should I use Climara? For detailed instructions, see the step- by- step instructions for using Climara at the end of this Patient Information. This area must be clean, dry, and free of powder, oil or lotion for your patch to stick to your skin. Do not use the same application site 2 times in the same week. If any adhesive residue remains on your skin after removing the patch, allow the area to dry for 1. Then, gently rub the area with an oil- based cream or lotion to remove the adhesive from your skin. This area must be clean, dry, and free of powder, oil or lotion. The same site should not be used again for at least 1 week after removal of the patch. For more information, ask your healthcare provider or pharmacist. Tell your healthcare provider if you have any side effects that bother you or does not go away. Call your doctor for medical advice about side effects. You may report side effects to Bayer Healthcare Pharmaceuticals at 1- 8. FDA at 1- 8. 00- FDA- 1. What can I do to lower my chances of a serious side effect with Climara? Apply immediately upon removal from the protective pouch. To throw away the patch, fold the sticky side of the patch together, place it in a sturdy child- proof container, and place this container in the trash. Used patches should not be flushed in the toilet. Do not use Climara for conditions for which it was not prescribed. Do not give the Climara patch to other people, even if they have the same symptoms you have. This leaflet summarizes the most important information about Climara. If you would like more information, talk with your healthcare provider or pharmacist. You can ask for information about Climara that is written for health professionals. For more information, go to www. Bayer Health. Care Pharmaceuticals Inc at 1- 8. What are the ingredients in Climara? Active ingredient: estradiol Inactive ingredient: acrylate copolymer adhesive, fatty acid esters, and polyethylene backing. Instructions for Use. Climara (Kl. There may be new information. This information does not take the place of talking to your healthcare provider about your menopausal symptoms or your treatment. You will need the following supplies: See Figure AFigure AStep 1: Pick the days you will change your Climara. You will need to change your patch 1 time each week or every 7 days. Remove the Climara patch from the pouch. See Figure B. . Remove the adhesive liner. See Figure C. . See Figure D. Do not remove the silver foil sticker from the pouch. See Figure E. Step 4. Placing the patch on your skin. See. Figure F and. Press the patch firmly onto your skin. If you cannot reapply the patch, apply a new patch to another area (See Figures F and G), and continue to follow your original application schedule. Used patches should not be flushed in the toilet. All rights reserved. Manufactured for: Bayer Health. Care Pharmaceuticals Inc. Whippany, NJ 0. 79. Manufactured by 3. M Drug Delivery Systems. Northridge, CA 9.
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